Vol. 4 No. 3 (2026)

Volume 4, Issue 3 features studies spanning clinical electrocardiology, tumor immunology, and regenerative medicine. A narrative review traces the historical evolution of calcium and hypocalcemia-associated clinical signs, from ancient observations to innovative contemporary ECG phenomena. A systematic review dissects the neuro-stromal-immune axis in triple-negative breast cancer, revealing how sensory nerve-derived CGRP signaling drives immune exclusion and immunotherapy resistance. A comparative review examines patient-derived and iPSC-derived organoid platforms, highlighting their complementary strengths in translational research and regenerative medicine. Together, the articles reflect the journal's commitment to publishing diverse research from clinical sign interpretation to molecular tumor microenvironment mechanisms and cutting-edge biomedical platforms with translational implications.